Hyderabad: New research has claimed that bacteria strains isolated from the Patancheru Waste Water Treatment Plant exhibit a high level of resistance against the antibiotics manufactured in the Patancheru bulk drug units.
The study also claimed that resistance exhibited by bacteria here was of the highest quantum noticed anywhere in the world. About 86 per cent of bacteria strains from Patancheru WWTP was found to be resistant to more than 20 types of antibiotics.
The Patancheru industrial cluster houses about 90 bulk drug units apart from other industrial units.
Resistant bacteria not easy to treat
Hyderabad: The Patancheru Enviro Tech Limited (PETL) is the common WWTP, which treats effluents from all the bulk drug units. Scientists said effluents from these bulk drug units treated at WWTPs had high bacterial densities alongside high concentrations of antibiotic drugs.
Such an environment, they said, was optimum for bacteria to develop resistance to the antibiotics. They lead to development of multi-drug resistance among disease-causing bacteria, which is several times more difficult to treat. For instance, patients of the Multi-Drug Resistant (MDR) Tuberculosis are non-responsive to most powerful TB drugs and alternative, more expensive drugs, with possible side effects, have to be used. Normally, resistance among humans is developed due to overuse of antibiotics.
“Waste-water treatment plants (WWTPs) serving antibiotic manufacturing industries may provide such spawning grounds given the high bacterial densities present there together with exceptionally strong and persistent selection pressures from the antibiotic-contaminated waste,” said a source.
Researchers from the National Centre for Cell Science (NCCS) and the University of Gothenburg in Sweden isolated about 93 strains of bacteria from the WWTP in Patancheru and studied their resistance patterns. Dr Yogesh Shouche of NCCS led the study along with Dr Nachiket Marathe and Dr Vidhuthalai Regina.
The bacterial strains were studied against 39 antibiotics. “All strains were resistant to at least five of the 39 tested antibiotics. About 86 per cent of the strains were resistant to 20 or more antibiotics, while 53 per cent of the strains were resistant to 29 or more antibiotics,” researchers said. adding, “To the best of our knowledge, the levels of multi-drug resistance exhibited by the strains in this study represent the highest reported from any environmental sample.”